Victor Guzov, Ph.D. in bioorganic chemistry, is a senior scientist at Monsanto Company’s research center in Cambridge, Massachusetts, where he leads the Protein Optimization and Evolution team. Victor has expertise in protein engineering and evolution, as well as mode of action of insecticidal proteins. He has been long involved in optimization of insecticidal proteins, for the purpose of protection of crop plants from insect damage and agricultural crop yield losses using biotechnology approaches at Monsanto Company. That lead him to research on mode of action of insecticidal proteins, and ways to assess their value for insect resistance management. His collaborative research with both industry and academic scientists on evolution of Bt proteins resulted in new opportunities for effective management of resistance to insect pests in genetically-optimized crop plants.