Nerissa brings deep academic, clinical research and biotechnology industry experience and she has held leadership roles in both clinical development and medical affairs at large, public and private, start-up biotechnology companies. Prior to AVROBIO, Dr. Kreher was the Global Head of Clinical and Medical Affairs at Zafgen, a clinical-stage biopharmaceutical company developing therapies for the treatment of metabolic diseases. In the role, she led the clinical team responsible for advancing the development of their lead program for Prader-Willi syndrome. Previously, she was Global Clinical Development Lead for Shire HGT and Executive Medical Director of Metabolic Disorders at Alexion Pharmaceuticals. Dr. Kreher began her career as Director, Medical Affairs at Serono and Medical Director at Genzyme. She received her M.D. from East Carolina University, her B.S. in biology from University of North Carolina at Chapel Hill and an M.S. in clinical research from Indiana University-Purdue University Indianapolis. Dr. Kreher holds an executive MBA from Northeastern University Graduate School of Business Administration.